Question 1

8.00  Registration Open

Accepted Answer

Welcome coffee.
Please enjoy breakfast at your hotel prior to arriving at the venue.

Question 2

9.00 - 11.05  PRE-CONFERENCE SESSION: Oligonucleotide Therapeutics Education Workshop

Accepted Answer

Co-chairs: 
Alex Garanto, Ph.D., Radboud Univ. Medical Center 
Audrius Kilikevicius, Ph.D., Eli Lilly and Company

9.00-9.25:         
Rewriting Genetic Information in RNA using Oligonucleotide-directed Adenosine Deamination, Peter Beal, Ph.D., UC Davis

9.25-9.50:         
Next-generation mRNA vaccines: New RNA modalities and delivery systems, Camilla Foged, Ph.D., University of Copenhagen

9.50-10.15:         
Improving the Safety and Specificity of RNAi Therapeutics, Maja M. Janas de Angelis, Ph.D., DABT, Alnylam Pharmaceuticals

10.15-10.40:          
Safety assessment of therapeutic oligonucleotides with focus on off-targets, Patrik Andersson, Ph.D., AstraZeneca

10.40-11.05:         
Early clinical development of nucleic acid therapeutics, Art Krieg, MD, Zola Therapeutics

Workshop sponsored by :
https://static.wixstatic.com/media/78cea0_8b4f948a28094ec98d2c13ffce7041d9~mv2.png

Question 3

11.15 - 13.00 Hosted Lunch & Mentorship Program Lunch

Accepted Answer

11.15 - 13.00
Hosted Lunch (for all participant)
Mentorship Program Lunch (by invitation only)

Question 4

13.00 - 14.40 PRE-CONFERENCE SESSION: Next-Gen Early Career Scientist Session

Accepted Answer

Co-chairs: 
Sarah Allen, Ph.D. Candidate, UMass Chan Medical School
Emilio Harris-Mostert, Ph.D. Candidate, Erasmus MC

Session Keynote:

13.00-13.25:   
Session Keynote: From Molecules to Meaning: An Academic Journey to ASO Therapies for Duchenne Muscular Dystrophy, Aurelie Goyenvalle, Ph.D., UMR-1179- University of Versailles, INSERM

13.25-13.40:
Dual-Peptide Strategy for Delivery of Therapeutic Oligonucleotides in Erythropoietic Protoporphyria, Angel Eduardo Santorelli Villamizar Ph.D., ETH Zurich

13.40-13.55:
Ligand Valency, Placement and Positioning Do Matter: Programmable Surface Modification of Rectangular DNA Origami Modulates Its Biological Activity, Natalia Navarro, IQAC-CSIC, CIBER-BBN, Barcelona, Spain
   
13.55-14.10:
Unraveling and controlling late-onset neurotoxicity of CNS-targeted antisense oligonucleotides through strategic chemical modifications, Takayuki Kuroda MD, NucleoTIDE and PepTIDE Drug Discovery Center, Institute of Science Tokyo

14.10-14.25:
Fatty acid mediated uptake system enables improved oligo delivery to muscle and brain, Argimiro Mayoral-Olmos, ARTHEx Biotech

14.25-14.40:
Immunoengineering of light-inducible RNA agonists enables spatiotemporal control of RIG-I activation for cancer immunotherapy, Sandra A. Lewash, University Hospital Bonn

Question 5

14.40 - 15.30 Refreshment Break

Question 6

15.30 - 16.45  OPENING SESSION AND KEYNOTE ADDRESS

Accepted Answer

Chair:
Richard Geary, Ph.D.,  Ionis Pharmaceuticals & President, OTS

15.30 - 15.45	Welcome and Opening Remarks

15.45 - 16.45	Keynote Presentation:
The Remarkable Versatility of Splice-Switching ASOs
Adrian R. Krainer, Ph.D., St. Giles Foundation Professor, Cancer Center Program Co-Leader

Question 7

16.45 - 18.15  CAREER EVENT

Accepted Answer

Co-Chairs: 
Eva-Maria Manz, Ph.D., ETH Zürich 
Jathavan Asohan, Ph.D. Candidate, McGill University

Panel discussion on diverse career paths in academia and industry.
Panellists:
Reka Haraszti, Ph.D., Universitätsklinikum Tübingen
Keith Gagnon, Ph.D., Wake Forest University
Graham Parker, Ph.D., Executive Editor, Mary Ann Liebert Inc.
Marc Lemaitre, Ph.D., Ph.D., ML_Consult Llc
Krystal Johnson, Ph.D, Alnylam Pharmaceuticals
Annabelle Biscans, Ph.D., AstraZeneca

Open to Students and Post-Docs.

Question 8

16.45 - 19.30  Welcome Reception with Exhibitors (no host Poster Viewing)

Accepted Answer

16.45 - 19.30
Welcome Reception with Exhibitors (no host Poster Viewing)

Question 9

20.00 - 22.00 Early Career Scientist Social Meet Up

Accepted Answer

Early Career Scientist Social Meet-up
(RSVP in the registration form - for students only)

Location:  EXTRA Bar 
Klauzál u. 15, 1072 Budapest | https://extrabudapest.com/en(https://extrabudapest.com/en)

sponsored by :
https://static.wixstatic.com/media/2be1ce_d112be889f3a40328f205f4750f8fb68~mv2.jpg

Agenda